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In addition, hyperphosphorylated Tau can suppress gene expression by recruiting histone deacetylases (HDACs) to condense chromatin structure (129)

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Y., Chiang, J

While it has shown promise in animal studies, its safety and efficacy in humans have remained uncertain due to a lack of robust clinical trials

Its research application in skin aging derives from its ability to modulate the SNARE complex, which facilitates acetylcholine release at the dermal-muscular interface