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For example, the active cysteine sites (Cys115 and Cys161) of CypA undergo oxidative modification to form intramolecular disulfide bonds, which contribute to the elimination of intracellular ROS

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A unique property of flavonoids and even flavonoid fragments is their ability to interfere with signaling pathways (e.g., Nrf2) and positively affect cellular processes involved in health and disease

It is a major peripheral inflammatory mediator

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10.1016/j.tjog.2013.06.020 4 AlimoradiN.FirouzabadiN.FatehiR