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The overall process involves a drug (CYP substrate) with a potentially oxidizable bond (X-H) binding the low-spin Fe 3 + (one unpaired electron S = , with a hexacoordinate metal centre including one water molecule) leading to a high-spin Fe 3 + (five unpaired electrons S = 5/2, pentacoordinate with no water, and a shortened Fe-S bond , pulling the iron slightly below the plane of the heme)

Osum M, Serakinci N

The most widely used materials in ELSIA are polystyrene and polyvinyl chloride

the preferred indication areas given above are to be supplemented with the following: chronic persistent or recurrent hepatitis

References Wu, F

Using 1 mL: This will create a more concentrated solution