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According to the NIH Office of Dietary Supplements, B12 supplementation does not improve athletic performance in athletes with sufficient B12 status. This statement, backed by decades of research, contradicts much of what youll hear in medical spa waiting rooms

This is important for severe anemia or neurological problems

GHK-Cu and AHK-Cu work at the cellular level and results take a few months

[1] Niacinamide in high doses can sometimes cause nausea, heartburn, or a sensation of warmth

common reactions include transient pain, erythema, or pruritus at the administration site, along with mild diarrhea, headache, or nausea in a minority of recipients

Waiting 15-20 minutes before any activity allows the queasiness to pass