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The microbiome-gut-brain content axis consists of three bidirectional, biochemical, signaling pathways between the gut and the brain, and these three pathways include the nervous, endocrine, and immune pathways (198)

doi: 10.1186/1471-2377-4-14
doi: 10.1016/S0140-6736(10)61889-2 235 KimJJLeeHMShinDMKimWYukJMJinHSet al

Individuals with heterozygous mutations are asymptomatic carriers with no clinical consequences

10.3389/fped.2020.585646 3 ChienY.-H.LeeN.-C.ChaoM.-C.ChenL.-C.ChenL.-H.ChienC.-C.et al (2013)
