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A study from The Netherlands (Riphagen, 2020) found that after 8.5 years of follow-up of an older cohort (median baseline age=65), a doubling of baseline MMA levels was associated with an increased risk of mortality (HR 11.48, CI 3.3239.64)
A strict vegan diet, age and long term use of antacid drugs & metformin may increase the chances of becoming deficient in Vitamin B12

Information on its individual components can be researched on public databases such as PubChem

NMO is diagnosed by a neurologist using a combination of clinical tests including MRI, lumbar puncture, blood and visual tests
