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Sphingomyelin is a type of sphingosine-containing phospholipid (sphingolipid) that is synthesized by the transfer of a phosphocholine residue from a phosphatidylcholine to a ceramide ( Figure 3 )

ED is the common underlying mechanism among different forms of TMAs, leading to the microvasculature thrombosis observed histologically (143)

Taguchi T, Takao T, Iwasaki Y, Pooh K, Okazaki M, Hashimoto K, Terada Y

Ann N Y Acad Sci 1365: 514 Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

doi: 10.1006/jmcc.2002.2050

Recent studies suggest that separate CNS mechanisms independent of a peripherally determined central sensitization may be complicated in pain, following glial damage (Taliyan & Sharma, 2012