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Pharmacological Profiles of Key Phytocannabinoids 2.1

Hence, enhancing G6PD activity might be the vital therapeutic method to prevent and treat diabetic complexities [215]

In subsequent studies using the same extract, the group also reported increased HDL-associated paraoxonase 1 (PON1) activity, plasma cGMP, and improved flow-mediated dilation, suggesting enhanced endothelial function via the NOcGMP pathway [164,165]

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Furthermore, resveratrol (RES), -glucan-chitosan nanoparticles (DS-CS NPs), and resveratrol-loaded sulfated -glucan-chitosan nanoparticles (DS-CS-RES NPs) could inhibit the release of NO, as well as the protein levels of NF-B, p65, STAT 1, and TLR 4, along with the secretion of inflammatory mediators such as TNF- , IL-6, and IL-1 in LPS-induced RAW 264.7 macrophages