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S5E) in SW48 +/G12D, confirming that the specificity and synergistic effects of MSO and CB839 depend on the heterozygous KRAS G12D allele
Engineered aging cardiac tissue Chip model for studying cardiovascular disease

Drugging RAS: know the enemy

The CM11-CM13 showed significant changes in gene expression related to glutathione metabolism, indicating that glutathione plays a crucial role not only in the detoxification of reactive oxygen species (ROS) during stress responses but also in the regulation of redox signaling, gene expression, and cellular defense mechanisms (Fig
