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The unintended effect of U0126 may be due to off-target inhibition of certain unknown enzymes required for ferroptosis, it might also be due to the anti-oxidative property of this compound as measured by its ability to reduce 2,2-Diphenyl-1-picrylhydrazyl (DPPH) (Figure S7B)
Little is known as to how ROS might regulate T cell development within the thymus
