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, Reference Sun2023), and their contribution to connected clusters

10.1007/s004310050746

Introduction Proton pump inhibitors (PPIs) are currently the most widely used acid-suppressive agents and are the first-line therapy for gastric acidrelated disorders, such as peptic ulcer disease, gastroesophageal reflux disease (GERD), and Barretts esophagus (Freedberg et al., 2017)

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Inhibition of lysyl oxidase can cause osteolathyrism, but, at the same time, its upregulation by tumor cells may promote metastasis of the existing tumor, causing it to become malignant and cancerous