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Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol

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Zafereo ME, Hanasono MM, Rosenthal DI , Sturgis EM, Lewin JS, Roberts DB, Weber RS

Most patients require treatment two to three times per week

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The numbers below come from two places: rodent studies scaled to a human size (allometric scaling) and several years of research community use reports