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However, no improvements in cognitive performance or retardation of cognitive decline have been observed (Rueda Revilla et al

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doi: 10.1074/jbc.273.13.7765 90 IshiiTMatsukiSIuchiYOkadaFToyosakiSTomitaYet al

Though an increased cellular GSH status is indicative of a plant's capacity to tolerate different stress pressures (Khan et al., 2009

Plant polyphenols such as quercetin exhibit strong antioxidative and anti-inflammatory activity by scavenging radicals, chelating metals, and activating the Nrf2ARE pathway, thereby upregulating antioxidant enzymes like SOD, catalase (CAT), and glutathione peroxidase (GPx)