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revealed that MSC-EVs promoted liver regeneration in fibrotic mice through enriched lncEEF1G, which acted as a competitive endogenous RNA by sponging miR-181a-5p, leading to upregulated HGF expression and release in HSCs [216]

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doi: 10.3389/fimmu.2025.1702860 Received 10 September 2025 Accepted 20 October 2025 Published 30 October 2025 Volume 16 - 2025 Edited by Jorge B

Although some studies have shown that zinc ion intake might suppress tumor growth, overwhelming reports focus on the promoting role of zinc in tumor initiation and development, or even driving metas44tasis

However, specific injuries such as traumatic brain injury, stroke, brain tumor, or aging are believed to compromise the efficiency of BBB protection, thereby allowing MSCs access to cross the BBB and deliver their protective effects