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Thus, senescent cells are causal for the reduction in renal function in fast aging Xpd TTD/TTD and naturally aged wildtype mice and by selective targeting of high-SASP expressing senescent cells in the tubuli, FOXO4-DRI can restore kidney homeostasis

However, higher maximal respiration (maximal oxygen consumption rate under high energy demand) and spare capacity (the difference between maximal and basal respiration) were observed in stretched ONH astrocytes compared to unstretched control cells, indicating an increased metabolic flexibility in glial cells during elevated intraocular pressure

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Endogenous Recovery after Brain Damage: Molecular Mechanisms that Balance Neuronal Life/death Fate

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Sharma D, Shrimal H, Singh K, Apparsundaram S, Dhobi M (2025b) Evaluation of the antiviral and anti-inflammatory activity of Acalypha indica L