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Am J Physiol Lung Cell Mol Physiol 301: L353360, 2011

For example, esculetin (20-60 mg/kg) can inhibit the production of inflammatory factors such as IL-1, IL-6, TNF-, C-C motif chemokine ligand 2 and iNOS in Escherichia coli-induced sepsis mice by inhibiting the NF-B and STAT1/STAT3 signaling pathways (95)

The following sources are referenced in this article: Andrews, Contemp Clin Trials Commun 2020 Bemis, Nutr Cancer 2005 Biegert, J Rheumatol 2004 Boe, Am J Orthop (Belle Mead NJ Brien, J Altern Complement Med 2006 Capodice, J Soc Integr Oncol 2009 Chantre, Phytomedicine 2000 Christensen, Osteoarthritis Cartilage 2008 Cuspidi, J Clin Hypertens (Greenwich Dai, BMJ 2017 Davidson, Arthritis Rheum 2013 Farpour, Evid Based Complement Alternat Med 2021 HMPC, 2016 Hausenblas, Cureus 2025 Hill, Nutrients 2023 Inaba, J Nat Med 2010 Kong Arthritis Rheum 2010 Kouraki, Nutrients 2026 Maddahi, Phytother Res 2023 Moura, Phytother Res 2017 Mller, J Transl Med 2023 Mller, Prostaglandins Leukot Essent Fatty Acids 2026 Nguyen, Cureus 2025 Oltean, Cochrane Database Syst Rev 2014 Schmid, Phytother Res 2001 Senftleber, Nutrients 2017 Loading Comments Submit your comment This feature is restricted to active members

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Abstract Background Cadmium (Cd), being a heavy metal, causes myriad clinical problems if exposed to the environment through food or drinking water or through inhalation

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