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Intriguingly, previous research demonstrated a functional partnership between the cells glutathione/glutathione disulfide (GSH/GSSG) balance and Atox1s redox state where GSH is able to reduce Atox1 and restore its ability to bind copper (Hatori et al., 2012)

doi: 10.6004/jnccn.2011.0016 151 GradisharWJAndersonBOBlairSLBursteinHJCyrAEliasADet al

These collective results strongly suggest a protective role for A
Iram et al., 2016

In addition to their catalytic activity, catalases can also function peroxidatively (Figure 3, step 3) to eliminate H 2 O 2 [45, 49]
