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Tang D, Chen X, Kroemer G

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Therapeutic Benefits: Matrix protein synthesis Stimulates collagen I, III, VII and elastin production Antioxidant amplification Enhances superoxide dismutase and catalase activity Tissue remodeling Balances collagen degradation and synthesis Vascular enhancement Promotes microcirculation and nutrient delivery Follicular activation Stimulates hair growth and scalp health Barrier optimization Strengthens skin protective mechanisms NAD+ (Nicotinamide Adenine Dinucleotide) Cellular Bioenergetic Optimizer NAD+ represents a paradigm shift in cellular anti-aging medicine, targeting the fundamental energy-producing mechanisms that govern cellular health, DNA repair, and metabolic function

Selective neuronal vulnerability to oxidative stress in the brain

Poem: Glaucoma The Silent Veil 2 Editorial Effectiveness of intraoperative periarticular infiltration in Total Hip Arthroplasty (THA): A clinical audit Plasmapheresis & Hemofiltration in poisonings Approach to seizures in children: A comprehensive review Total Parenteral Nutrition Dancing Dragons: A tale of 2 Intriguing Cases Multifocal Giant Cell Tumor of the Wrist: Radiologic-Pathologic Correlation and Review of Diagnostic Challenges Aortic Dissection: A case report Bullous Pemphigoid: A case report Chondromyxoid fibroma excision and bone grafting: A case report Insights from Diabetes on Wheels: A community-based screening An intriguing challenge of unveiling the unexpected: Peripartum cardiomyopathy ECMO: The last resort for refractory beta-blocker overdose Giant Cell Tumor of talus in a 14-year-old child treated by curettage and cementation: A case report Parquet poisoning survival: A rare triumph over a deadly herbicide Pituitary Apoplexy with Hypopituitarism: A rare presentation with refractory hyponatremia Type 3c Diabetes Mellitus secondary to chronic calcific pancreatitis Tuberous sclerosis complex: When Genes Go Off Script Spinal stability restored: A case of odontoid fracture post-trauma An ultra-short series of hand replants in quick succession First successful neonatal percutaneous cardiac intervention done in Maa Kauvery & Heart city, Trichy

Figure 4 Low GH and low IGF-I Like acromegaly, GHD can be considered as a primary GH disorder, where changes on the GH/IGF-I axis are reflected by a primary association with low GH and low IGF-I ( Table 1
