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Protein misfolding and failure of clearance systems, including the autophagy-lysosome and ubiquitin-proteasome pathways, further compromise the cellular environment and lead to toxic intracellular accumulations [31, 32]

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[12] One hypothesis is that BPC-157-associated modulation of nitric oxide biology may influence VEGFR2-axis signaling and endothelial organization

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Furthermore, through the pentose phosphate pathway, a metabolic pathway parallel to the glycolysis pathway, cells can produce ribose-5-phosphate (a five-carbon sugar), which is a precursor for the pentose sugars seen in the RNA and DNA structure, as well as glycerol-3-phosphate for phospholipid synthesis [94]

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