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Total n-3 unsaturated fatty acid levels and DHA concentrations significantly increased and total n-6 polyunsaturated fatty acids and AA levels significantly decreased in the motor cortex of the PD mice model heavily fed DHA, and both striatal dopamine levels and tyrosine hydroxylase immunoreactivity were observed to increase and increase, respectively
10.3390/jcm11133573 J Clin Med
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In addition, EDV regulates the hypothalamicpituitaryadrenal (HPA) axis via downregulation of FK506 binding protein 5 (FKBP5), a protein involved in glucocorticoid receptor (GR) trafficking to the nucleus, which may contribute to normalization of stress-induced abnormalities in the HPA axis (Herbet et al., 2019)
10.1038/nature23283 54 JuarezE
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