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Immunotherapy can be achieved by either manipulating the patients immune cells using internal resources or by stimulating the immune system through external resources [13]

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Keywords: hair, early graying, premature graying, PHG, hair pigmentation Introduction Early graying, also known as premature hair graying (PHG), is defined as the loss of natural hair color before the typical onset of gray hair

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Our data suggest that GCLM KO mice have higher capacities for ethanol and acetaldehyde clearance, which may contribute to the protective phenotype