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Restani, P., Campagner, P., Fiecchi, A., Resmini, P

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(4) Bile acids contribute to the guts antimicrobial defenses through direct bacteriostatic actions of bile acid-fatty acid mixed micelles and by signaling to induce expression of antimicrobial genes, thereby reducing small bowel bacterial translocation and intestinal inflammation

Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism

10.1016/b978-0-444-64057-4.00009-0 [DOI] [Google Scholar] Sun W., Wang S., Zhao W., Wu C., Guo S., Gao H., et al

These epigenetic alterations may impair transcription factor recruitment and alter expression of drug-metabolizing genes such as CYP1A1, ultimately impacting drug metabolism and pharmacokinetics (Wang et al., 2018)