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In addition, stress, humidity, and low temperatures increase the sensation of pain [121]

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Sci Rep 14 , 20553 (2024)

Its a triagonist , meaning it activates three key receptors: GLP-1, GIP, and glucagon

Generally, the strongest candidates are adults with a body mass index of 30 or higher, which falls into the obese category, or adults with a BMI of 27 or higher who also have at least one weight related comorbidity