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Intrathecal delivery of an adeno-associated viral vector serotype 9 (AAV9)-human SURF1 (hSURF1) has effectively corrected biochemical abnormalities in mouse models of SURF1 deficiency (107)

Overall, the quality was highly variable

, 291 , 22861-22867, doi: Li, B., Qiu, B., Lee, D

Additionally, in this same study a mutant virus with other IE proteins deleted were assessed in order to determine if ICP27 alone was sufficient to activate p38 and JNK

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Hal Scofield is a physician-scientist at the Oklahoma Medical Research Foundation, and he also serves as associate chief of staff for research at the Oklahoma City VA Medical Center