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A potent and selective small-molecule Lp(a)-reducing therapeutic could provide a way to decrease the number of primary and/or secondary major adverse cardiovascular events in patients who are at risk of cardiovascular disease because of their high levels of Lp(a)

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Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance

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When doses get lower, smaller steps (2.5 to 5 percent) may feel more manageable