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The results suggest that high level of CYP2E1 can increase mitochondrial function damage in vivo stimulated by DXR (Fig

10.1161/01.CIR.0000161797.67671.A7 Circulation 90 StevensA.BegumG.CookA.ConnorK.RumballC.OliverM.et al (2010)

Hao Y, Zhang Z, Han D, Cao Y, Zhou P, Wei Z, Lv M, Chen D

Cutting edge: role of macrophage migration inhibitory factor in inhibiting NK cell activity and preserving immune privilege

Activation of this pathway by CoQ10 can lead to increased neuronal resilience against various stressors, including excitotoxicity and inflammation
It works hand in hand with COQ10 to help quench oxidative stress within the mitochondria
