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Molecular informatics 30 , 614622, (2011)

As science continues to unravel the mysteries of aging, Epitalons role will likely become clearer

This molecule, also known as -tocotrienol quinone, exerts its effect on the activity modulation of oxidoreductases, in particular NQO1, resulting in increased cellular glutathione (GSH) concentration and improvement of the REDOX status

Kampranis, S.C., Damianova, R., Atallah, M., Toby, G., Kondi, G., Tsichlis, P.N

By inhibiting NNMT, 5-Amino-1MQ reduces 1-MNA formation and alleviates the methyl sink, increasing SAM availability for other methylation reactions, while freeing nicotinamide for recycling through NAMPT toward NAD

In order to have a better understanding of ROS testis neutralization or limitation by the antioxidant systems, we summarize the major pathways of ROS generation and the mechanistic antioxidative defense in Figure 1