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Supported by an increasing number of studies these effects suggest the involvement of IGF-1 in metabolism coordination [136]

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Mechanistically, PCDHB14 is induced by p53, and increased PCDHB14 downregulates the expression of SLC7A11, which is mediated by accelerated p65 protein degradation resulting from PCDHB14 promoting E3 ubiquitin ligase RNF182-mediated ubiquitination of p65 to block p65 binding to the promoter of SLC7A11 (Liu Y

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2012;Dec 20;367(25):2419-2426

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Yoshioka et al., 2017)

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However, the exact number of sessions will be determined by Dr

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