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Indicaes e Resultados Esperados

doi: 10.4103/0028-3886.391388 25

Pdiatrische Patienten (Pharmakokinetik bis zu einem Alter von 12 Jahren): Die Pharmakokinetik von Topiramat bei Kindern ist wie bei Erwachsenen, die eine Add-on Therapie erhalten, linear mit einer von der Dosis unabhngigen Clearance und Steady-State-Plasmakonzentrationen, die proportional zur Dosis ansteigen

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Findings from the discovery cohort also identified numerous proteins that are associated with acute inflammation, redox balance and immune responses such as ORM1, ORM2 and Afamin (AFM) that were elevated in konzo affected children, perhaps identify additional future targets of investigation 44,45,46