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The extracellular matrix is a dynamic scaffold that provides structural support while also serving as a reservoir of growth factors and signalling molecules

Store reconstituted peptides at 2-8C (standard refrigerator temperature) for short-term use, typically within 2 to 4 weeks

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The HLA molecule, normally found on the antigen-presenting cell (APC), attachs and reveals an antigenic peptide, enabling the T cell to recognize and respond to an antigen

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We used a four-week protocol to induce acute demyelination in wildtype (WT), R1.40 and APP/PS1 as illustrated in Fig