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The underlying biological phenomenon involves ROS, which play a complex dual role in sperm physiology and pathology

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J Am Coll Nutr 14:229232 Costanigro M, Appleby C, Menke SD (2014) The wine headache: consumer perceptions of sulfites and willingness to pay for non-sulfited wines

However, the ligand-binding pocket exhibited two unique structural features that were not observed in previously determined GPCRs