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B12 affects brain and nervous system functions, and a deficiency can cause clinical depression

These associations were independent of demographic, socioeconomic, lifestyle factors, use of medications that could have an effect on serum vitamin B12 levels, dietary supplement use and fasting time

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Fourth, a peptide that binds to an intracellular target protein can be combined with a peptide that binds to an E3 ligase to degrade the target protein via proteolysis targeting chimera (ProTac) technology