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Results, safety, and dosing remain unproven in human populations

In a double-blinded randomized trial, neither the researchers nor the participants know which group they belong to

While a number of longitudinal studies indicate inverse correlation between T2DM and neurodegeneration, a cohort study of 4651 T2DM patients with 12-year follow up, Metformin treatment was associated with increased risk of Parkinsons disease, Alzheimers disease and all-cause dementia

Ultimately, understanding your body and working with a trusted provider is the best path forward

This manifests as cramping, bloating, or vague upper abdominal fullness

In addition to helping patients with type 2 diabetes control their blood sugar, tirzepatide recently received positive results in a Phase 3 clinical trial for the treatment of generally obese individuals who do not have type 2 diabetes