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The majority of inflammatory hepatocellular adenomas demonstrated perivascular and/or patchy glutamine synthetase staining (73.6%), while the remaining cases had diffuse (7.5%), negative (3.8%), or patchy pattern of staining (15%) that showed subtle differences from the classic map-like staining pattern and was designated as pseudo map-like staining

In sorafenib-treated hepatocellular carcinoma (HCC) cells, autophagy was activated to inhibit apoptosis and mediate cellular chemoresistance [136], but sorafenib also induced autophagy-dependent ferroptosis in HCC cells [130]

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Medications that stimulate the CYP system can predispose patients to APAP hepatotoxicity by causing enhanced production of NAPQI via the oxidative pathway

Utilization of one-carbon groups derived from glycine for cellular methylation reactions may be important in other cancer cell types