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References Rodgers RJ et al

This uncertainty is one of the challenges with using compounds that lack regulatory approval

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Novel small molecule inhibitors of nicotinamide N-methyltransferase (NNMT)
Vitamin B6 assists the process of synthesizing compounds into chemical messengers called neurotransmitters

The NNMT-blocking mechanism of 5-amino-1MQ has been shown to increase levels of the cofactor NAD+, whose replenishment in organisms promotes muscular, cognitive, and immune function, as well as increased lifespan [4, 5]
