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Levothyroxine is a medication that is generally taken for life to maintain normal thyroid function

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When levels drop, melanin production becomes less regulated, leading to dark spots, uneven tone, and reduced radiance

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BCKAs can be metabolized by BCKDH to branched-chain acyl-CoA, and blocking this step causes serious metabolic disorders, such as maple syrup urine disease (Xu et al., 2020) and propionic academia (Chen et al., 2017)

GSE also significantly reduced pain, bony spurs, and joint damage in osteoarthritic mice, improving collagen levels and reducing cartilage loss