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10.3390/ijms17122000 22 DavisS

By forming the TP53-HIPK2-AXIN1 complex, HIPK2 (Homeodomain-interacting protein kinase-2) can control the creatine kinase and transcriptional activation of TP53 (Tumor protein 53)

Clinical trials found no associated increase in arrhythmias or adverse cardiovascular events

doi: 10.1158/1055-9965.EPI-20-0743 118 SouleSKingJAMillarRP

The oxidative stress and inflammation biomarkers can be looked at as surrogate markers of the ultimate clinical response

The PDI was used to quantify the extent of dispersion, distribution of size, and vesicle size uniformity within a sample 31