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KPV, as a small tripeptide, has a very short plasma half-life of approximately 10-15 minutes but exerts intracellular anti-inflammatory effects that outlast its plasma window

Or, they do, but the body isnt able to absorb enough vitamin B12 from food

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Additionally, the findings reveal that DSIP-CBBBP crosses the blood-brain barrier more effectively than traditional peptides, potentially enhancing its efficacy in vivo

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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Vukojevi J., Vrdoljak B., Malekinui D., Siroglavi M., Milavi M., Kolenc D., Blagai A.B., Batelja L., Drmi D., Seiverth S., et al