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Bal-Price and Brown demonstrated similar finding using astrocytes and microglia exposed to LPS or interferon- in which blocking nitric oxide (NO) production induced by the inflammatory cytokines, prevented neurotoxicity.[14] Further, they found that the NO rapidly inhibited mitochondrial respiration and this increased glutamate release from neuronal/astrocytic cultures

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10.1016/j.stemcr.2019.09.002 27 DaiY.GuoJ.ZhangB.ChenJ.OuH.HeR

Human suction blister fluid composition determined using high-resolution metabolomics

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