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doi: 10.1016/0968-0004(90)90216-x
18 ,

An ATF4-CHOP cascade is involved in the induction of ChaC1 under ER stress conditions, which results in the accelerated degradation of intracellular glutathione and may be responsible for cell death

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[DOI] [PMC free article] [PubMed] [Google Scholar] Mao Y

In addition, FAM134B induces ER-phagy to directly degrade calmodulin and CNX and attenuates mitochondrial Ca 2+ damage [50, 51]