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1 , 209 In addition, non-invasive monitoring of on-target lipid peroxidation or ferroptosis pathway engagement remains underdeveloped and should be incorporated into early-phase trials to enable pharmacodynamic decision-making

d.VroomenM.WijnandsE.et al (2018)

This toxic process contributes to cardiac dysfunction, leading to cardiomyopathy, heart failure, and pulmonary hypertension because of repeated injury to cells [64,65,66,67], among other complications

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Studies show BPC-157 stabilizes existing vascular structures and modulates vascular tone via nitric oxide-mediated vasodilation, safeguarding tissues against ischemic damage during repair processes

Therefore, GST activity results in irreversible GSH depletion leading to decreased levels of GSH if not to de novo GSH biosynthesis