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Similarly, urate is also neuroprotective by enhancing GSH expression through activation of the Akt/GSK3/NRF2/GCLC pathway in mutant SOD1 G85R cellular and Drosophila models (Zhang et al., 2019b)

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2011;301:C739748

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After blood collection, the mice were euthanized by cervical dislocation, and their ovaries and uteri were immediately removed

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