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Specific roles of different PRDX isoforms in tumor-promoting, tumor-suppression as well as tumor treatment resistance have been reviewed previously for different cancers [106] with a number of specific applications to different cancer types including for example breast [107], lung [108] or pancreatic cancers [109]

Specific PHGDH inhibitors exhibit lower toxicity and a wider therapeutic window by targeting tumor-specific modification sites (135)

Beyond serving as a risk factor, T2DM has been shown to worsen disease progression and increase symptom severity in PD [65]

Supplemental Figure 10

Glutathione is a redox molecule, that is, it can be in oxidized form and reduced form

In some studies 1,2 the use of NAC to reduce COPD (chronic obstructive pulmonary disease) was investigated in more detail and some of the symptoms were reduced
