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Neuropsychopharmacology 39:27422749 Cavalcante DP, dos Santos Nunes A, Silva ER, de Carvalho GA, Chiarelli RA, Oliveira-Lima OC, Leoncini GO, Ulrich H, Gomez RS, Pinto MCX (2024) GlyT1 inhibition promotes neuroprotection in the middle cerebral artery occlusion model through the activation of GluN2A-containing NMDAR

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Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism at Baylor

doi: 10.1128/mbio.03798-24 124 SkovgaardO

Nicotine acetylcholine receptors (nACHRs) (Ni et al., 2013) and using an antagonist of 7nAChR can actually inhibit the proliferation of microglia and reduce the expression of inflammatory factors IL-1 and TNF- (Poorthuis et al., 2009), improves neuronal plasticity in the hippocampus (Motaghinejad et al., 2016), and can treat excitotoxicity at low concentrations (Sieber, 2012)