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As in many other skin diseases, the role of the oxidant/antioxidant system could also be relevant in the pathogenesis of pemphigus

Human Foreskin Fibroblast (HFF-1) Cell Culture The HFF-1 cell line (ATCC-SCRC-1041) was cultured in DMEM, supplemented with 12% (v/v) FBS, 100 IU/ml penicillin and 100 g/ml streptomycin

Clinically, this would lead to unpredictable results, with the day-to-day efficacy of the supplement varying wildly with the food consumed by the patient

& Singh, A

Glutathione is a potent endogenous antioxidant found in virtually all body cells
PDI oxidation by Ero1 leads to the production of ROS (Gross et al , 2006)