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Description
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Though a patient can sometimes recall an injury of some sort to the penis preceding the problem, usually during sexual activity, it most commonly forms spontaneously in men having less firm but still useful erections

Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])

PMID 18824827

Acad Emerg Med 2001, 8: 999-1001

HY: Methodology, Project administration, Writing review & editing
