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Retrieved from Briggs, G

Cerebrospinal fluid concentrations rise within approximately 30 minutes of an intranasal dose and are reported to reach roughly 60 to 70 percent of corresponding plasma concentrations in rodent studies, a striking ratio for a peptide of this size

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ED30 values were 2.11 0.81 mg/kg for tesofensine and 6.36 2.21 mg/kg for 5-HCP/CB

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