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Compaction of DNA with histone proteins protects the molecule from inadvertent unwinding and copying

McCarthy RC, Kosman DJ

This process causes its oligomerization and accumulation in the form of senile plaques in the brain cortex, hippocampus, and other brain areas

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Studies have shown that binding of adenosine to A2A receptors can inhibit T cell receptors and lead to inactivation of T cells, thereby reducing inflammation levels and tissue damage (Ochaion et al., 2008)
