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As per studies, a diet high in carbohydrates increases acid reflux time and causes more reflux symptoms, while a low carbohydrate diet has the opposite effect

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Among these oncometabolites, 2HG has gained prominence due to its chiral forms, D -2HG and L -2HG, which structurally mimic -KG and competitively inhibit -KG-dependent dioxygenases

PMID: 83 BaptissartMVegaAMartinotEPommierAJHoutenSMMarceauGet al