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In eighteen relevant perioperative NAC meta-analyses, nine investigated the effect of NAC on renal function in cardiac surgery as the primary objective [33,35,37,38,41,44,47,48,66], three discussed general NAC use in cardiac surgery with frequent mention of renal outcomes [40,45,49], and two focused on renal outcomes in noncardiac surgery [43,46]

Barton ER

PLoS One 9 , e115922 (2014)

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The cumulative mortality was observed for 21 days and the relative percent survival (RPS) was calculated